What this section (Tox21) hopes to achieve

The field of toxicology has been around for centuries. But in our modern world, it is more important than ever before. There are 80,000 chemicals in the environment today, and, in the U.S. alone, roughly 2000 new chemicals are being produced every year. However, only 10% of all existing chemicals have been tested and, of these, only 3% extensively tested.

Additionally, a vast majority of testing was and is being done on animals. How similarly do animals and humans react to chemicals? Is the time and billions of dollars we spend on animal testing worth it? And is it even ethical to use so many animals for toxicity testing? The importance of these questions were properly realized only a decade ago, with the publication of National Academy of Sciences report on Toxicity Testing in the 21st Century.

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The report which changed toxicology. Image source: National Academy of Sciences

This section will largely cover this report and talk about new emerging technologies and methods in toxicology. It is also touch upon an up-and-coming discipline called Evidence-Based Toxicology.

Unlike most fields, toxicology hasn’t progressed with the times and is still largely rooted in 20th century concepts and methods. For the field to remain relevant, it is important it advances to the 21st century. However, as John Maynard Keynes said,

“The difficulty lies not so much in developing new ideas as in escaping from old ones.”
I hope you enjoy the topics in this section as much as I do!

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